葉伯壽

職稱:助理教授
國立清華大學生命科學系博士
署立新竹醫院神經科主任 
neuron.nthu@gmail.com
開設課程:神經科學導論

學經歷

  • M. d., Taipei Medical University (1986)
  • Master, National Tsing Hua University, Life Science college, (1998)
  • Ph.d., National Tsing Hua University, Life Science college, (2009)
  • Fellow / Visiting Professor in neurosonology, department of neurology, Wake forest university school of medicine (July-sep, 2004)

歷任職稱

  • 臺大醫院新竹分院部主任
  • 臺大醫院新竹分院神經部醫師
  • 國立交通大學資工系合聘助理教授

專長領域

【專長領域】

  • 神經科學
  • 醫學
  • 分子與細胞生物

【研究計畫】

  • 104年衛生福利部長照資源不足地區建置失智症社區服務計畫–優等
  • 104科技部計畫:Tau蛋白正子掃描像在偵測輕度認知功能障礙及阿茲海默症預測能力之前瞻性研究
  • (A pioneer study of new Tau protein PET imaging agent in detection of mild cognitive impairment and Alzheimer’s disease)
  • 104科技部計畫:認知功能衰退之流行病探討:心臟及腦血流動力學與短長期營養調控機制研究–遠期和近期營養及化學不平衡狀況對於老人大腦認知功能的影響: 「營養過盛」、「營養不良」、及代謝異常所扮演的角色The Long-Term and Short-Term Nutritional Status or chemical imbalance and Elderly Cognitive Function: the Roles of Over-Nutrition, Malnutrition and Aberrant Metabolism
  • 103科技部計畫計:腦血管硬化與血流動力學對認知功能的影響The impact of Cerebral Arteriosclerosis and Hemodynamics on Elderly Cognitive Function: the Aspect of Blood Supply and Circulation
  • 103科技部計畫:微型核醣體對心腦交互作用及大腦認知功能的調控與分子機轉The Regulation and Molecular Mechanism of MicroRNA in Cardio-cerebral Interaction and Cognitive Impairment

論文著作 / 通識相關活動紀錄

  • SCI Impact of coexisting coronary artery disease on the occurrence of cerebral ischemic lesions after carotid stenting.PLoS ONE PLoS One 2014 14;9(4):e94280. Epub 2014 Apr 14.
  • Kuo-Lun Huang, Yeu-Jhy Chang, Chien-Hung Chang, Ting-Yu Chang, Chi-Hung Liu, I-Chang Hsieh, Ho-Fai Wong, Yau-Yau Wai, Yu-Wei Chen, Bak-Sau Yip, Tsong-Hai Lee
  • SCI Carotid Artery Stenting Improves Cerebral Hemodynamics Regardless of the Flow Direction of Ophthalmic Artery.AngiologyAngiology 2014 Feb 24. Epub 2014 Feb 24.
  • Chi-Hung Liu, Chien-Hung Chang, Ting-Yu Chang, Kuo-Lun Huang, Jr-Rung Lin, Yu-Wei Chen, Bak-Sau Yip, Shan-Jin Ryu, Yeu-Jhy Chang, Tsong-Hai Lee
  • SCI Correlations between membrane immersion depth, orientation, and salt-resistance of tryptophan-rich antimicrobial peptides.Biochim. Biophys. Acta Biochim Biophys Acta 2013 Nov 27;1828(11):2720-8. Epub 2013 Jul 27.
  • Hui-Yuan Yu, Bak-Sau Yip, Chih-Hsiang Tu, Heng-Li Chen, Hung-Lun Chu, Ya-Han Chih, Hsi-Tsung Cheng, Shih-Che Sue, Jya-Wei Cheng
  • SCI Proteinuria independently predicts unfavorable outcome of ischemic stroke patients receiving intravenous thrombolysis.PLoS ONE PLoS One 2013 22;8(11):e80527. Epub 2013 Nov 22.
  • Chih-Hao Chen, Sung-Chun Tang, Li-Kai Tsai, Shin-Joe Yeh, Kai-Hsiang Chen, Chen-Hua Li, Yu-Jen Hsiao, Yu-Wei Chen, Bak-Sau Yip, Jiann-Shing Jeng
  • SCI Boosting salt resistance of short antimicrobial peptides.Antimicrob. Agents Chemother.
  • Antimicrob Agents Chemother 2013 Aug 28;57(8):4050-2. Epub 2013 May 28.
  • Hung-Lun Chu, Hui-Yuan Yu, Bak-Sau Yip, Ya-Han Chih, Chong-Wen Liang, Hsi-Tsung Cheng, Jya-Wei Cheng
  • SCI.The thermostable direct hemolysin from Grimontia hollisae causes acute hepatotoxicity in vitro and in vivoPLoS ONE PLoS One 2013 21;8(2):e56226. Epub 2013 Feb 21.
  • Yan-Ren Lin, Yao-Li Chen, Keh-Bin Wang, Yi-Fang Wu, Yu-Kuo Wang, Sheng-Cih Huang, Tzu-An Liu, Manoswini Nayak, Bak-Sau Yip, Tung-Kung Wu
  • SCI Rational design of tryptophan-rich antimicrobial peptides with enhanced antimicrobial activities and specificities.ChembiochemChembiochem 2010 Nov;11(16):2273-82
  • Hui-Yuan Yu, Kuo-Chun Huang, Bak-Sau Yip, Chih-Hsiang Tu, Heng-Li Chen, Hsi-Tsung Cheng, Jya-Wei Cheng
  • SCI Easy Strategy to Increase Salt Resistance of Antimicrobial Peptides Antimicrobial Agents and Chemotherapy (AAC) Yu HY, Tu CH, Yip BS, Chen HL, Cheng HT, Huang KC, Lo HJ, Cheng JW (co 1st author). (published online) 2011 .
  • SCI Research Paper Site-Directed Mutations of Thermostable Direct Hemolysin from Grimontia hollisae Alter Its Arrhenius Effect and Biophysical Properties
  • Yu-Kuo Wang1*, Sheng-Cih Huang1*, Yi-Fang Wu1, Yu-Ching Chen1, Yen-Ling Lin1, Manoswini Nayak1, Yan Ren Lin1, Wen-Hung Chen1, Yi-Rong Chiu1, Thomas Tien-Hsiung Li2 , Bo-Sou Yeh3, and Tung-Kung Wu1 Int. J. Biol. Sci 2011; 7(3):333-346.Biochemistry & molecular biology
  • SCI AHA/ASA GetWith The Guidelines –Stroke Performance Indicatorsnacross Nations: Surveillance of Stroke Care in the Taiwan Stroke Registry Fang-I Hsieh*, PhD; Li-Ming Lien*, MD; Sien-Tsong Chen, MD; Chyi-Huey Bai,PhD; Mu-Chien Sun, MD, MSc; Hung-Pin Tseng, MD; Yu-Wei Chen, MD;Chih-Hung Chen, MD; Jiann-Shing Jeng, MD, PhD; Song-Yen Tsai, MD, MSc;Huey-Juan Lin, MD, MPH; Chung-Hsiang Liu, MD, MSc; Yuk-Keung Lo, MD; :Han-Jung Chen, MD, PhD; Hou-Chang Chiu, MD; Ming-Liang Lai, MD; Ruey-Tay Lin, MD; Ming-Hui Sun, MD; Bak-Sau Yip, MD, PhD; Hung-Yi Chiou, PhD; ChungY. Hsu, MD, PhD and Taiwan Stroke Registry Investigators (CIRCULATION 122(11):1116-1123 2010-9)
  • SCI Rational Design of Tryptophan-Rich Antimicrobial Peptides with Enhanced 4. Antimicrobial Activities and Specificities . ChemBioChem Volume 11, Issue 16, pages 2273–2282, November 2, 2010 Hui-Yuan Yu 1,†, Dr. Kuo-Chun Huang 1,†, Dr. Bak-Sau Yip 1,2,†, Chih-Hsiang Tu1, Dr. Heng-Li Chen1, Hsi-Tsung Cheng1, Dr. Jya-Wei Cheng1 Article first published online: 23 SEP 2010
  • SCI Increased potency of a novel d-beta-naphthylalanine-substituted antimicrobial peptide against fluconazole-resistant fungal pathogens”, FEMS Yeast Research, (2009) PMID 19538482 Volume 9, Number 6, September 2009 , pp. 967-970(4) (SCI) Wang CW, Yip BS, Cheng HT, Wang AH, Chen HL, Cheng JW, Lo HJ,”
  • SCI Solution structure and model membrane interactions of P-113, a clinically active antimicrobial peptide derived from human saliva”, JCCS 2009 56, 961-966 (SCI) Bak-Sau Yip, Heng-Li Chen, Hsi-Tsung Cheng, Jiun-Ming Wu, and Jya-Wei Cheng.

開設課程

  • 神經科學導論(一)
  • 神經科學導論(二)
  • 健康醫療系統之人因工程
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